POEM@home
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Introduction
Proteins are the machinery of all known cellular life. Amazingly, these large biomolecules with up to 100,000 atoms fold into unique three-dimensional shapes; these shapes determine each protein's function.

But the shape of a protein is very difficult to determine experimentally. So POEM@HOME implements a novel approach to determining protein structure computationally. (The scientific approach behind POEM@HOME is based on the thermodynamic hypothesis that won C. B. Anfinsen the Nobel Prize in Chemistry in 1972.)

By joining this project you will help to

  • predict the biologically active structure of proteins
  • understand the signal-processing mechanisms by which proteins interact with one another
  • understand diseases related to protein malfunction or aggregation
  • develop new drugs on the basis of the three-dimensions structure of biologically important proteins

Contents

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Videos

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Science

[The Science section might (or might not) be divided into two parts: {1} general discussion of the field, and then {2} a discussion of the project's specific endeavor. For instance, in LHC@home, we might have {1} "Science of the Large Hardon Collider" and then {2} "Science of LHC@home"

The above is desirable, because in most cases, the field of research is really fascinating, and presenting this in broad terms-- outlining the big questions-- can make it easier to understand the particulars of the project and why it is important.]

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Results

[Where known, we should attempt to keep track of each project's publications. A good list to draw from is here. ]

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Links of Interest

[Why recreate the wheel; there are lots of great sources out there.; a good list of sources can be really useful to the reader.]

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POEM@home In the Classroom

[For each project, please add a "[Projectname] in the Classroom" section-- with a link to Volunteer Computing In the Classroom and an article named "[Projectname] in the Classroom". (Then please add "[Projectname] in the Classroom" to the list on the main Education page.)]

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