What do you have in the next menu Activity:

You have to select "run based on preferences"

The same for the GPU if you have GPU capabilites.

And for the preferences use grid republic to set them.

So delete the local preference you have made.

After a change on grid republic you have to synchronise with the boinc client, in the tool Menu.

Hi,

You can adjust the memory preferences in your user profile

go to http://boinc.bakerlab.org/rosetta/prefs.php?subset=global

and edit the section "Disk and memory usage"